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Windows Server 2012 Login Issue "The User Profile Service service failed the sign-in. User profile cannot be loaded."

Whenever I try to login to our Exchange Server, I receive the following error:

"The User Profile Service service failed the sign-in. User profile cannot be loaded."

The issue affects more than one user.

Relevant Info:

Server Version: 2012 Datacenter

Exchange Version: 2013

The Exchange server is virtualized.

What I’ve tried:

1) Remote Desktop from a workstation on the network

2) Remote Desktop from Virtual Machine Manager

3) Connect via console from Virtual Machine Manager

4) Accessing the server via Computer Management and adding my user account to Allow Login via Remote Desktop

5) Creating a new user account for myself by copying the account of a user who can get in

6) Rebooting

I’d appreciate any suggestions.

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